MerMade™ oligo synthesizers enable organisations to bring DNA and RNA oligonucleotide synthesis in-house while maintaining control over production schedules, quality processes and supply continuity. As part of the Biosearch Technologies end-to-end oligo synthesis portfolio, MerMade systems are supported by phosphoramidites, synthesis reagents, columns and consumables designed for oligonucleotide production workflows. The portfolio spans benchtop, parallel-column and high-throughput plate-based platforms, supporting synthesis scales from nanomole to millimole quantities. Instrument configurations can be tailored to specific throughput requirements and support a broad range of standard, degenerate and chemically modified oligonucleotides for molecular diagnostics, genomics, synthetic biology and therapeutic development applications.
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Scalable oligo synthesis platforms for research and production workflows
Configurable DNA and RNA synthesis systems supporting diverse throughput, scale and modification requirements
Expert support for in-house oligonucleotide manufacturing
Supporting organisations with instrument selection, system configuration, installation, training and ongoing technical support.
Who we support
Laboratories and organisations evaluating in-house DNA and RNA oligonucleotide synthesis. Requirements may vary based on throughput, synthesis scale, workflow needs and preferred production formats. Organisations assessing instrument footprint, laboratory setup and production requirements before implementation.
What they need
Guidance throughout instrument selection, custom configuration, installation and operation to support successful oligonucleotide manufacturing workflows. Training during installation, together with online technical support, preventative maintenance and service contract options, helps maximise instrument uptime and long term productivity.
Applications, technologies and markets enabled by
oligo synthesis
Applications
MerMade-produced oligonucleotides support PCR, qPCR, NGS library preparation, CRISPR workflows, molecular diagnostics, synthetic biology, gene synthesis and nucleic acid therapeutics development.
Technologies
MerMade systems employ automated solid-phase phosphoramidite chemistry and support synthesis of standard, degenerate and chemically modified oligonucleotides using a broad range of phosphoramidite building blocks.
Featured Resources
Featured Resources
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Why choose Biosearch Technologies MerMade™ oligo synthesizers
Configurable synthesis platforms backed by a complete oligo synthesis ecosystem.
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Global impact
37,000+
Customers supported worldwide
Reach
144
Countries served globally
Frequently asked questions
How much does an oligo synthesizer cost?
Pricing varies depending on the selected MerMade™ system, throughput requirements, synthesis scale and configuration options. Contact our team to discuss your requirements and request a quotation.
Which MerMade model suits my throughput?
Instrument selection depends on daily oligo volume requirements, format preferences and synthesis scale.
What oligo lengths are supported?
All MerMade synthesizers can produce oligos in the 20-60 nucleotide range.
What training is required?
Typical operator training requires approximately three to four days following installation.
When should synthesis be brought in-house?
Organisations may consider in-house synthesis when supply security, turnaround time and workflow control are priorities.
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Ready to evaluate MerMade?
Discuss your throughput, synthesis scale and workflow requirements with our team to identify the MerMade™ oligo synthesizer best suited to your laboratory.
MerMade™ oligo synthesizer portfolio comparison
Compare MerMade platforms by throughput, synthesis format and production capacity.
Choose the right MerMade™ oligo synthesizer for your throughput needs
Instrument | Throughput | Format | Positioning |
MerMade 4 | Low-Medium | 4 Columns | Entry-level in-house synthesis |
MerMade 6 | Medium | 6 Columns | Flexible benchtop synthesis |
MerMade 12 | Medium | 12 Columns | Expanded parallel synthesis |
MerMade 48X | High | Multi-column platform | Higher throughput production |
MerMade 96E | High | 96-well format | Parallel oligo synthesis |
MerMade 192E | Very High | Dual 96-well format | Efficient high-throughput production |
MerMade 192X | Very High | High-capacity platform | High-throughput for complex oligos |
MerMade Pharos 768 | Ultra High | 768-well platform | Ultra-high-throughput production |
MerMade Azimuth 768 | Ultra High | 768-well platform | Flexible and high-throughput |